To avoid loss of vital genetic information, the tiny cells in our body must accurately segregate their DNA into two daughter cells each time they divide. This complicated process is called “cell division” and usually works fine. However, sometimes errors happen giving rise to daughter cells with unequal or damaged DNA, which can lead to unchecked cell proliferation and cancer. By investigating the mechanisms of cell division, the Zachos’ lab aims to understand the origins of carcinogenesis and devise novel ways to specifically stop cancer cells from dividing to improve cancer treatment.

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